Advanced results

Advanced results

Advanced results

Advanced results

Why choose Spectrum?

All preimplantation genetic screening (PGS) tests are not created equal. In fact, only Natera’s PGS utilizes SNP microarray technology powered by our exclusive Parental Support™ bioinformatics. This provides more comprehensive embryo aneuploidy results.

Product features

Calculated accuracies are reported for each chromosome pair in each embryo sample; a calculated accuracy greater than 99% is typical for each chromosome call. Full 24-chromosome aneuploidy screening is performed on every sample. Spectrum also provides comprehensive detection:

  • Haploidy/Triploidy
  • Uniparental disomy
  • Parental origin of aneuploidies
  • Confirmation of correct parentage
  • Sample contamination from non-embryonic DNA
  • Large deletion/duplication detection
  • Simultaneous PGS and preimplantation genetic diagnosis (PGD)

Product support

  • Streamlined user experience through Natera Connect, our HIPAA-compliant portal
    • Track patient test status
    • Electronically generate an embryo manifest for enhanced quality control
    • Obtain genetic counselor notes and patient results
  • Support from experienced board-certified genetic counselors available for you and your patients

Product features

Calculated accuracies are reported for each chromosome pair in each embryo sample; a calculated accuracy greater than 99% is typical for each chromosome call. Full 24-chromosome aneuploidy screening is performed on every sample. Spectrum also provides comprehensive detection:

  • Haploidy/Triploidy
  • Uniparental disomy
  • Parental origin of aneuploidies
  • Confirmation of correct parentage
  • Sample contamination from non-embryonic DNA
  • Large deletion/duplication detection
  • Simultaneous PGS and preimplantation genetic diagnosis (PGD)

Product support

  • Streamlined user experience through Natera Connect, our HIPAA-compliant portal
    • Track patient test status
    • Electronically generate an embryo manifest for enhanced quality control
    • Obtain genetic counselor notes and patient results
  • Support from experienced board-certified genetic counselors available for you and your patients

Product features

Calculated accuracies are reported for each chromosome pair in each embryo sample; a calculated accuracy greater than 99% is typical for each chromosome call. Full 24-chromosome aneuploidy screening is performed on every sample. Spectrum also provides comprehensive detection:

  • Haploidy/Triploidy
  • Uniparental disomy
  • Parental origin of aneuploidies
  • Confirmation of correct parentage
  • Sample contamination from non-embryonic DNA
  • Large deletion/duplication detection
  • Simultaneous PGS and preimplantation genetic diagnosis (PGD)

Product support

  • Streamlined user experience through Natera Connect, our HIPAA-compliant portal
    • Track patient test status
    • Electronically generate an embryo manifest for enhanced quality control
    • Obtain genetic counselor notes and patient results
  • Support from experienced board-certified genetic counselors available for you and your patients

Product features

Calculated accuracies are reported for each chromosome pair in each embryo sample; a calculated accuracy greater than 99% is typical for each chromosome call. Full 24-chromosome aneuploidy screening is performed on every sample. Spectrum also provides comprehensive detection:

  • Haploidy/Triploidy
  • Uniparental disomy
  • Parental origin of aneuploidies
  • Confirmation of correct parentage
  • Sample contamination from non-embryonic DNA
  • Large deletion/duplication detection
  • Simultaneous PGS and preimplantation genetic diagnosis (PGD)

Product support

  • Streamlined user experience through Natera Connect, our HIPAA-compliant portal
    • Track patient test status
    • Electronically generate an embryo manifest for enhanced quality control
    • Obtain genetic counselor notes and patient results
  • Support from experienced board-certified genetic counselors available for you and your patients

A unique methodology  

Natera’s SNP microarray PGS with Parental Support offers unique benefits over other testing methods. Natera’s 24-Chromosome Aneuploidy PGS screens all 24 chromosomes with an accuracy that is typically at least 99%. This is significant because aneuploidy can involve any chromosome, so methods that only test some of the chromosomes or that do not detect certain types of chromosome problems are at risk of missing important genetic information. Accuracy is critical to avoid discarding normal embryos or transferring abnormal embryos.

 

Cross-referencing data for the best results

Spectrum is run on a 300,000 probe SNP microarray platform with Parental Support technology. Parental Support is a set of proprietary molecular and bioinformatics methods that uniquely measure single nucleotide polymorphisms (SNPs). Parental Support uses data obtained from three SNP microarrays and the Human Genome Project to calculate each embryo sample result. Our bioinformatics capabilities allow us to compute per-chromosome confidence calls to assess the chromosome constitution of each embryo sample. This method enables Natera to return highly accurate and comprehensive results for each embryo sample. Parental Support technology is the only PGS method that compares embryo data with parental genomic information, also incorporating data from the Human Genome Project and using sophisticated bioinformatic algorithms.

What factors affect single-gene PGD accuracy?

Many scenarios can affect the accuracy of single-gene PGD and cause misdiagnosis. Natera’s Parental Support addresses these problems by using a microarray testing platform with Parental Support bioinformatics. The accuracy of Natera’s single-gene PGD testing is usually greater than 99%.

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